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When you exercise, your muscles release special proteins called myokines that help communicate with your immune system. One of these proteins is called IL-6. During exercise, IL-6 helps reduce inflammation, which is important because ongoing inflammation is linked to the development and survival of cancer. IL-6 triggered by exercise also encourages the body to produce other substances that calm inflammation.
However, IL-6 can sometimes behave differently depending on where and how it’s made. But when it comes from your muscles during exercise, it helps keep inflammation under control and supports your overall health.

Myokines help regulate the immune system, modulating immune cell activity. During exercise, myokines help enhance the immune system's ability to respond to infections, while simultaneously preventing excessive inflammation. The release of myokines like IL-6 and IL-15; triggered by exercise, has been linked to improved immune surveillance, which is highly beneficial in the fight against cancer.